The liver is a very huge organ in the body. It normally weights between 1-1.33 kilograms, and is about a football size. It is wedge-shaped, reddish-brown and sits immediately under the diaphragm on the right side of the upper abdomen. The liver has more than 40 functions which are essential for supporting life and another over 500 minor functions. Therefore, the liver is the most crucial organ in the body and we can't live without it. In addition, the liver has a special ability to reproduce new tissues to substitute for the damage ones.

The liver is capable of working very hard and has a lot of patience. Although it is damaged in some parts, it would give no sign of being damaged until more than 80% of its working ability is reduced. Symptoms showing damages of the liver are indigestion, bloated stomach, bitter tastes, yellow skin, pale excrement, and lower right ribs ache, etc. This is probably because the liver doesn't stay in motion. It doesn't beat like the heart or make a noise like the bowel. Thus, many people think it is not very important.

One of the major roles of the liver is to detoxify drugs or waste from the body.

The toxins after filtered that can be dissolved in the water will be removed through the kidney and the ones dissolved in fat will be excreted together with the bile.

The detoxification of drugs can be divided into 2 phases.

Waste from metabolism or any unwanted chemical compounds that the body receives are sent to the liver to be removed. Thus, the body is being cleaned at all times. To conclude, the function of detoxification of the liver is very essential to one's health and life.

The liver detoxifies drugs in 2 phases and these 2 phases must be completed one by one in order to remove toxins from the body.

Phase I detoxification of most chemical toxins involves a group of enzymes which, collectively, have been named cytochrome P450. These enzymes catch the toxins from blood and prepare it for the removal. It is like when we have to pack things before mailing it to someone.

In this phase, the toxins are converted to a more chemically active form. They can be both free radicals, ready to destroy the liver, and cancer-causing agents, ready to do harm to the tissues in the body. Thus, the process of detoxification can't just stop at phase I. Phase II must also be completed in order to make a real detoxification.

If the liver finishes phase I but can't get rid of the toxins in time in phase II, a person will feel like taking some sleeping pills; sleepy, lifeless, lazy, and exhausted.

Phase II detoxification typically involves conjugation in which various enzymes in the liver attach small chemicals to the toxin. This conjugation reaction either neutralizes the toxin or makes the toxin more easily excreted through the urine or bile.

Substances that activate Phase I detoxification are caffeine, phenobarbital, and alcohol. Therefore, coffee enema can only half stimulate the liver to work.

Nutrients needed by phase II detoxification enzymes are sulfur, glutathione, limonene, systeine, benzoic acid, vitamin B complex, magnesium, selenium, and zinc. These nutrients will activate the liver to work in phase II so that the detoxification can be complete. Hence, every time we do the coffee enema we must activate our body to get rid of the toxins in phase II by always eating red-unpolished rice, green vegetables, beetroot, broccoli, all kinds of cabbages (cauliflower, purple cabbage, star cabbage, onion, white lettuce, reddish, curcuma longa)

Herbs that activate toxins detoxification are ginseng, dandelion, milk thristle and artichoke, etc.

Since the process of detoxification also needs activate agents such as caffeine for phase I and foods for phase II, we should always keep in mind that coffee enema can only half help.

If you want to make the detoxification complete you must also take foods that cooked with very green vegetables, cabbages, white lettuce, onion, and curcuma longa.